Boston's players were already en route to Cleveland when they learned of the explosions near the Boston Marathon's finish line that killed three and injured more than 170. The Red Sox were hoping to bring some relief to those affected by the tragedy, and they may have while winning their fourth straight.
The series opener was also Indians manager Terry Francona's first game against the Red Sox, the team he led to two World Series titles during eight seasons in Boston.
Helped by five walks, the Red Sox scored seven runs in the second off Ubaldo Jimenez (0-2) and gave Felix Doubront (1-0) all the support he needed.
Staked to the big lead, Doubront allowed two runs and four hits in five innings. He struck out seven.
Monday's tragic events in Boston brought a somber tone to Francona's reunion as well as to the Red Sox. Before the game, in a clubhouse devoid of its usual pregame sound and bustle, several players spoke of how a memorable Patriots Day win over Tampa Bay turned horrific.