The Nets (30-22) ended a five-game losing streak at Bankers Life Fieldhouse and won for just the second time in six games overall despite playing without injured guard Deron Williams. Joe Johnson added 17 points, and Reggie Evans had eight points and 22 rebounds.
Indiana (31-21) lost its second straight home game in overtime, following a 15-game home winning streak. George Hill scored 22 points and Roy Hibbert added 12. Jeff Pendergraph had a season-high 14 points.
It was an unusual night for the Pacers. All-Star forward Paul George was just 1 of 10 from the field and finished with five points before fouling out with 1:03 to play. David West left the game after 60 seconds and did not return in the second half after getting poked in the eye by Lopez. And Indiana's suddenly strong offense bogged down and shot just 34.4 percent from the field.
Williams missed the game with synovitis, an inflammation of the ankle joint linings, receiving platelet rich plasma treatment on both ankles. He's unlikely to return until after the All-Star break. His absence put even more of a burden on Lopez, who responded to the challenge by getting the struggling Nets offense off to a roaring start.
Indiana trailed 65-56 early in the fourth quarter, but appeared to swing the game with a 7-0 run in which Hill and Hibbert accounted for all the points to give the Pacers a 76-72 lead with 1:38 to play.