After another brutal attack in the mountains on Sunday, Froome leads Bauke Mollema and Alberto Contador by more than four minutes with only six stages left -- four of them suited to him. There is a time trial on Wednesday, followed by three straight days of tortuous climbs in the Alps.
But winning looks like the easy part.
The 28-year-old Froome's physical superiority at the 100th Tour has raised eyebrows, practically inevitable in the climate of suspicion that haunts cycling after Lance Armstrong was stripped of his seven titles for serial doping.
This year's race is the first since Armstrong lost his titles, and Froome understands the tone of the questions. Still, he was unhappy that doping became a main topic of his news conference on Monday's rest day. That followed his stage win on Mont Ventoux, a mammoth climb in Provence that he tamed with two blistering attacks and where he left Contador -- the 2007 and '09 Tour champion -- lagging behind.
"I just think it's quite sad that we're sitting here the day after the biggest victory of my life ... quite a historic win, talking about doping," Froome said. "Here I am basically being accused of being a cheat and a liar and that's not cool.
"To compare me with Lance, I mean, Lance cheated. I'm not cheating. End of story."
With so many of cycling's recent exploits later shown to have been drug-assisted, people understandably want to know whether they should continue believing. Froome's performances are subject to intense debate on social media, cycling blogs and in mainstream media.
"I can assure you that we are thinking very, very hard about the optimal way of proving to you guys that we're not doping," Sky team manager Dave Brailsford said Monday, adding that the World Anti-Doping Agency could help by appointing an expert to scrutinize Froome.
"They can come and live with us," Brailsford said. "They can have all of our information. They can see all of our data."
Brailsford and Froome would much rather be focusing on the Alps.
And judging by what Contador saw on the 21-kilometer (13-mile) ascent up Ventoux, the Spaniard has every reason to fear more misery there.
"My objective was to win the Tour, but (Froome) is a level above the rest," Contador said.
If Contador thinks Ventoux was tough, then he will be dreading Thursday's 18th stage -- featuring two big climbs up l'Alpe d'Huez, one of the Tour's most famed mountain passes.
That is bad enough, but Friday's 204.5-kilometer (127-mile) trek from Bourg d'Oisans to Le Grand-Bornand looks horrendous.
There is simply no respite.
The day begins with two massive climbs, known as HC (Hors Categorie, essentially meaning they are beyond classification because they are so tough) and finishes with two nasty Category 1 climbs, a level just below HC but still incredibly hard.
For good measure, Saturday's stage ends with a 10.7-kilometer (6.6-mile) HC climb up to Semnoz.
Froome, however, remains wary of Contador.
"There are a lot of very eager racers in the peloton left with a lot still to prove," Froome said. "For us it's about keeping the yellow jersey and riding in whatever way we can to best defend (it). I don't think we are necessarily on a mission to try and win every mountain top finish."