Sysco is buying privately held US Foods for about $3.5 billion in cash and stock.
When the deal closes, Sysco expects the addition of US Foods to boost its annual sales by about 46 percent to around $65 billion.
Sysco Corp. has a distribution center in Halfmoon and US Foods has an operation in Clifton Park, both in Saratoga County.
In October, US Foods purchased Quandt's Foodservice Distributors of Amsterdam, one of the region's last independent food service distributors.
Quandt's is scheduled to close its Amsterdam operation early next year.
At the time of the Quandt's announcement, the approximate 110 employees were told by US Foods representatives that employment options could exist for those willing to make the drive to the Clifton Park facility.
Sysco shares rose almost 10 percent Monday and hit their highest point in decades.
Houston's Sysco will pay $3 billion in common stock and $500 million in cash. It will also assume or refinance about $4.7 billion in debt.
That puts the total value of the deal at about $8.2 billion.
Sysco President and CEO Bill DeLaney said that the two companies have highly complementary core strengths including large product portfolios.
For the fiscal year that ended in June, Sysco's sales totaled $44.41 billion.
It trucks food and cooking supplies to about 425,000 customers through 193 locations in the U.S., Bahamas, Canada, Ireland and Northern Ireland.
US Foods' customers include independent and chain restaurants, health care and hospitality companies, and government and educational institutions.
Major stakeholders in the company, based just outside of Chicago, in Rosemont, Ill., include Clayton, Dubilier & Rice LLC and Kohlberg Kravis Roberts & Co. LP.
Representatives from both of those investment firms will join Sysco's board.
When the deal closes, US Foods shareholders will own about 87 million shares, or about 13 percent, of Sysco's common stock.
The buyout has been approved by the boards of both companies.
Sysco said it expects the deal, which is set to close in the third calendar quarter of 2014, to immediately boost its profit after adjusting for acquisition-related costs and expenses.
It's also expected to create annual cost savings of at least $600 million after three or four years.
Moody's Investors Service placed all of Sysco's ratings, including its investment-grade "A1" long-term rating, under review for possible downgrade.
Moody's said that while the deal makes sense and the price seems fair, a downgrade is likely given the amount of debt Sysco will assume.
Sysco shares rose $3.31, or 9.7 percent, to close at $37.62. The stock peaked earlier Monday at $43.40, its highest point since at least 1985.
It's up 19 percent this year.